Problematic opioid behaviors are dynamic and time-limited, new research finds

Problematic opioid behaviors are dynamic and time-limited, new research finds

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Problematic opioid use behaviors are usually dynamic and time-limited, a brand new research by researchers on the Nationwide Drug and Alcohol Analysis Centre (NDARC), UNSW Sydney has discovered.

Researchers analyzed 5 years of survey knowledge from 1,514 adults who have been prescribed opioids for continual non-cancer ache (CNCP).

Lead creator, Scientia Professor Louisa Degenhardt mentioned, “The findings problem a standard view that the danger of opioid-related behaviors is static and that threat evaluation initially of opioid therapy can predict which sufferers will develop opioid use dysfunction.”

“Affected person monitoring must be ongoing, as extramedical use or considerations could generally happen. Monitoring instruments to foretell threat could also be improved by contemplating dynamic elements, corresponding to fluctuations in ache severity and interference, ache self-efficacy, melancholy, and anxiousness.”

The research examined the prevalence, incidence, cessation, and persistence of 4 opioid use behaviors and three indicators of extramedical use and hurt.

“These behaviors weren’t secure inside people over time and usually solely occurred one or two factors throughout 5 years of follow-up,” mentioned Scientia Professor Degenhardt.

“This implies that even amongst a cohort of individuals with lengthy standing CNCP, long run opioid use, and a number of bodily, psychological well being, and substance use dysfunction comorbidities, indicators of problematic opioid use are dynamic and time-limited—not continual and recurring.”

The research additionally revealed essential findings on opioid cessation.

“In sufferers with CNCP who’re utilizing opioids for long-term ache administration, a minority ceased opioids in any interview, and this additionally modified all through interviews,” mentioned Scientia Professor Degenhardt.

“The findings recommend some people with a protracted historical past of opioid use for CNCP don’t keep a constant sample of opioid use.”

“These people who report ceasing their opioid use have been much less more likely to categorical concern about its adversarial results on their lives and functioning and reported having a larger capability to deal with ache.”


Hashish use seems to encourage, not substitute, non-medical opioid use


Extra info:
Louisa Degenhardt et al. Pharmaceutical Opioid Use Patterns and Indicators of Extramedical Use and Hurt in Adults With Persistent Noncancer Ache, 2012-2018, JAMA Community Open (2021). DOI: 10.1001/jamanetworkopen.2021.3059

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Nationwide Drug and Alcohol Analysis Centre (NDARC)

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Problematic opioid behaviors are dynamic and time-limited, new research finds (2021, April 14)
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